Even though not commonly lethal when taken on your own, a diazepam overdose is taken into account a medical unexpected emergency and usually calls for the fast attention of health care personnel. The antidote for an overdose of diazepam (or any other benzodiazepine) is flumazenil (Anexate). This drug is only Employed in circumstances with extreme respiratory despair or cardiovascular troubles. For the reason that flumazenil is a brief-acting drug, and the results of diazepam can last for days, a number of doses of flumazenil could be important.

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Valium works by facilitating the exercise of your chemical GABA at several receptor internet sites within the brain. GABA lessens action in various areas of the brain, including areas that assistance Manage emotion, considered, memory, and automatic features for instance respiratory.

Your doctor will come to a decision the ideal dose of diazepam to suit your needs. It is vital to acquire diazepam particularly as your medical doctor lets you know to.

tecovirimat will improve here the amount or outcome of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Observe. Tecovirimat is actually a weak inhibitor of CYP2C8 and CYP2C19. Check for adverse results if coadministered with sensitive substrates of such enzymes.

conivaptan will raise the stage or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.

fluconazole will boost the stage or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

If you take diazepam often and overlook to have a dose, take the skipped dose once you try to remember, Except if It is approximately time in your next dose. In cases like this, just depart out the missed dose and acquire your next dose at the usual check here time.

Some possible companies get drug exams during the interviewing system to monitor for doable drug misuse. Or, a doctor may want to verify you don't have traces of Valium as part of your program just before prescribing One more medication.

phenobarbital will check here lessen the level or outcome of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

It can be utilised to treat anxiety, muscle mass spasms and seizures or matches. It's also Utilized in hospital to lower Liquor withdrawal signs, like perspiring or trouble sleeping.

methylprednisolone will lessen the extent or result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.

Successful therapies may entail tapering your dosage to handle withdrawal indications together with psychotherapeutic methods which include cognitive-behavioral therapy and contingency management.

triclabendazole will boost the amount or effect of diazepam by impacting hepatic enzyme CYP2C19 metabolism.